Renin-Angiotensin System in Aortic Aneurysm

Renin-angiotensin system and unilateral ureteral obstruction

Unilateral ureteral obstruction (UUO) is a clinical scenario that leads to obstructive nephropathy. UUO alters the expression of many mediators in the ipsilateral kidney. Renin-angiotensin system (RAS) is involved in UUO. Angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7) as the main arms of RAS influence kidney function which may alter by UUO. Ang II via Ang II receptor subtypes I (AT1R) ...

Renin-Angiotensin System Inhibition for Aortic Stenosis⁎

In the developed world, aortic stenosis (AS) is the most prevalent valvular heart disease and, after hypertension and coronary artery disease, the most common heart disease overall in Europe and North America (1). In the elderly, the prevalence of AS has been reported to be between 2% and 9% (2,3). Aortic sclerosis, the precursor of AS, has been found in 29% of subjects older than 65 years (4)....

Is there a new target in the renin-angiotensin system for aortic aneurysm therapy?

Renin - Angiotensin - Aldosterone System

Chronic heart failure (CHF) is associated with endothelial dysfunction. Activation of the renin-angiotensin-aldosterone system (RAAS) is believed to be important in the deterioration of endothelial dysfunction in CHF through stimulation of oxidative stress. Whereas angiotensin-converting enzyme inhibitors (ACE-I) improve endothelial function in CHF, the effects of angiotensin II AT 1-receptor b...

Renin - Angiotensin - Aldosterone System

http://jra.sagepub.com/content/10/1/24 The online version of this article can be found at: DOI: 10.1177/1470320309104067 2009 10: 24 Journal of Renin-Angiotensin-Aldosterone System Manuel Labiós, Marcial Martínez, Francisco Gabriel, Victoria Guiral, Francisco Dasi, Belén Beltrán and Anna Muñoz patients: effects of eprosartan treatment Superoxide dismutase and catalase anti-oxidant activity in l...